Das Enzym Cyclooxygenase-2 als Vermittler der proapoptotischen Wirkung von Cannabinoiden und Chemotherapeutika auf humane Tumorzellen
- Eichele K, Ramer R, Hinz B (2009) R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. Pharm Res 26:346-55
[Abstract] - Eichele K, Ramer R, Hinz B (2008) Decisive role of cyclooxygenase-2 and lipocalin-type prostaglandin D synthase in chemotherapeutics-induced apoptosis of human cervical carcinoma cells. Oncogene 27:3032-44
[Abstract] - Eichele K, Weinzierl U, Ramer R, Brune K, Hinz B (2006) R(+)-methanandamide elicits a cyclooxygenase-2-depependent mitochondrial apoptosis signaling pathway in human neuroglioma cells. Pharm Res 23:90-4
[Abstract] - Hinz B, Ramer R, Eichele K, Weinzierl U, Brune K (2004) R(+)-methanandamide-induced cyclooxygenase-2 expression in H4 human neuroglioma cells: Possible involvement of membrane lipid rafts. Biochem Biophys Res Commun 324:621-6
[Abstract] - Hinz B, Ramer R, Eichele K, Weinzierl U, Brune K (2004) Upregulation of cyclooxygenase-2 expression is involved in R(+)-methanandamide-induced apoptotic death of human neuroglioma cells. Mol Pharmacol 66:1643-51
[Abstract] - Ramer R, Weinzierl U, Schwind B, Brune K, Hinz B (2003) Ceramide is involved in R(+)-methanandamide-induced cyclooxygenase-2 expression in human neuroglioma cells. Mol Pharmacol 64:1189-98
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